

PROPOLIS M.E.D.®
for INTIMATE HEALTH
- Antioxidant activity
- Antinflammatory activity
- Antibacterial activity
- Antiviral activity
Propolis M.E.D.®, thanks to its activity against microorganisms involved in vaginal infections, thanks its antioxidant and antinflammatory activities, thanks its mucohadesive and acid properties is a good ingredient in supplements or medical devices as adjuvant in treatment of vaginal infections or maintaining the natural balance in vaginal and urinary tract health.
Scientific evidence
7 number of published articles on Propolis M.E.D.®
6 of research institutes involved in scientific research
STUDIES ABSTRACTS
Propolis has been described as a promising alternative and complementary nutraceutical as it has multiple therapeutic properties including antimicrobial, antinflammatory, antiseptic, antitumor, immunomodulatory, wound healing, anesthetic, and antioxidant actions (Zaccaria et al., 2017; Lupion et al. 2013; Oliveira-Júnior et al. 2017).
Despite its complexity, the biological activity against VVC seems to be well defined. Capoci et al. (2015) demonstrated the antifungal activity of propolis on C. albicans and its inhibition of biofilm formation as possible preventive therapeutic strategies for VVC.
The best alternative includes propolis that reduce the population of the infectious agent, restore the balance of the microbiota, reestablish pH and promote repopulation by lactobacilli, act to relieve the signs and symptoms, or even eliminate the infection (Papa et al. 2017).
For these reasons, the antibacterial activity of Propolis M.E.D.® and it’s proved antinflammatory and antioxidant activity (as previously discussed: Zaccaria et al 2017, Curti et al 2019, Zaccaria et al 2019), the low pH (pH<5 in all extracts), the no activity against Lactobacillus spp., suggest using the characterized polyphenol complex as alternative therapy to cure and to maintain the health of vaginal tract.
A recent study (Demir et al. 2020) showed that different estracts of standardized propolis preparation (M.E.D.®) with glycol, ethanol, glycerol and soya oil, were found having potent antiviral activity against herpes simplex type 2 (HSV-2) virus.
Features

ORGANIC

OGM FREE

ADDITIVE FREE

GLUTEN FREE

KOSHER

SUGAR FREE

LACTOSE FREE
Thanks to the patented method of extraction developed by B Natural, we are able to provide many different forms of our extracts, all with the same consistent standardized polyphenol complex, responsible for clinically proven activity.
ESIT®
microencapsulated powder extract
Powder standardized extract, obtained through a microencapsulation process of Propolis M.E.D.® mother extract with Arabic gum
CHARACTERISTICS
- Powder extract
- Mild taste masking of propolis
- Free flowing powder
ADVANTAGES
- Easy to formulate in solid dosage forms
- Good flow and compressibility (not sticky)
- Highly stable even at high temperature (up to 180 °C)
- No preservatives needed
- Hydro-dispersible
APPLICATIONS
- All solid formulation
TITRATION AVAILABLE
- 12% total polyphenol complex expressed as Galangin
- 6% total polyphenol complex expressed as Galangin
- 3% total polyphenol complex expressed as Galangin
GREIT®
hydroglyceric extract
Hydroglyceric standardized extract, obtained processing Propolis M.E.D.® mother extract with glycerin
CHARACTERISTICS
- Liquid extract
- Good taste
- Ethanol free
- Suitable for children
ADVANTAGES
- Easy to formulate in water based formulation
- Can be used without flavoring agent
- Highly stable
- No preservatives needed
APPLICATIONS
- All water based liquid formulation
TITRATION AVAILABLE
- 12 mg/mL total polyphenol complex
- 6 mg/mL total polyphenol complex
- 3 mg/mL total polyphenol complex
POLE®
oily extract
Oily standardized extract, obtained processing Propolis M.E.D.® mother extract with vegetable oil (sunflower or soybean)
CHARACTERISTICS
- Liquid extract
- Ethanol free
- High polyphenol load
ADVANTAGES
- Ready to use for soft gels
- Highly stable
- No preservatives needed
APPLICATIONS
- Softgels
- Vaginal suppository
- Cream
TITRATION AVAILABLE
- 30 mg/mL total polyphenol complex